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GIP receptor signaling GIP is secreted by intestinal K cells after nutrient ingestion and, like GLP-1, stimulates glucose-dependent insulin secretion

Hamrick MW, Pennington C, Newton D, Xie D, Isales C

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During chronic infections, increased levels of proinflammatory cytokines such as TNF-, IFN- and IL-6 together with increased CD8 T cell activation can trigger muscle catabolism and even cachexia, promoting the degradation of muscle proteins for energy or amino acids (178180)

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