Sham-operated rats underwent the same surgical procedure except for the MCA occlusion
Functioning as a potent exercise mimetic, this small-molecule compound enhances mitochondrial function, fatty acid oxidation, and oxidative muscle fiber composition, thereby improving exercise endurance, cardiac metabolic efficiency, and systemic energy expenditure without increasing food intake 1-4
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Acute lipolytic effects from AOD-9604 begin within 90 minutes of injection, but measurable body composition changesdefined as 23% reduction in body fat percentagetypically require 68 weeks of consistent daily administration combined with caloric deficit and exercise
Presented for research literature review only Chen BL et al