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In vitro and in vivo models, it was found that in the IDH1 mutant glioma cells intervened by triptolide, the transcriptional activity of Nrf2 was suppressed, and the expressions of GCLC, GCLM and SLC7A11 were down-regulated, thereby disrupting the metabolism of glutathione
Lift the object toward the ceiling, then bend and straighten at the elbow only
Animal studies suggest benefit, but human data are minimal
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12 Commonly, patients may experience gastrointestinal disturbances such as nausea, vomiting, diarrhea, and constipation
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