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SLC25A19 transports ThPP 21 , the critical cofactor for the E1 subunit of the mitochondrial pyruvate dehydrogenase complex (PDC) and oxoglutarate dehydrogenase complex (OGDC) (Supplementary Fig
It is approved to treat neurological disorders such as seizures and neuropathic pain
Liver biopsy for histological assessment: the case against
A.YolandaR.ZitaM.TheresiaS.AstiaraniY.SantiB
Unlike its DAC-conjugated counterpart, Modified GRF (1-29) does not contain the Drug Affinity Complex (DAC) , resulting in a shorter biological half-life but a more natural pulsatile GH release pattern that mimics the bodys physiological secretion rhythm
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