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Strategy five: slower dose titration to allow metabolic adaptation The standard tirzepatide titration schedule increases the dose every four weeks
Orskov C, Rabenhoj L, Wettergren A, Kofod H, and Holst JJ
Different metabolic pathways
In the years before biosimilar entry, AbbVie invested aggressively in building out its immunology pipeline acquiring Allergan for $63 billion in 2020, a transaction that added Botox, Juvederm, and a range of non-Humira products to the portfolio [30]
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