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A 95 , 647654 (2019)
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Copper serves as an essential cofactor for over a dozen so-called cuproenzymes, including superoxide dismutase (SOD) for antioxidant defense, lysyl oxidase for collagen cross-linking, and cytochrome c oxidase for cellular respiration
Curculigoside has been found to provide support for GPX4 expression, thus protecting against ferroptosis in a manner that depends on selenium (22)
The compound binds HGF with sub-nanomolar affinity (Kd 65 pM) and is investigated as a synaptogenic research molecule with notable properties unusual for a peptide: oral bioavailability and blood-brain barrier permeability
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