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97 Several regulators of microglial phagocytosis have been identified, including but not limited to tyrosine kinase-binding protein (TYROBP), 98 triggering receptor expressed on myeloid cells 2-apolipoprotein E (TREM2-APOE) pathway, 99,100 spleen tyrosine kinase (SYK), 101,102 classical complement system, 103 purinergic system, 104 sialic acid binding immunoglobin-like lectins (Siglecs) (CD22 and CD33), 105,106,107 TAM system, 77 and mechanosensor Piezo1

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De aanbevolen startdosering is 3 mg per dag gedurende 30 dagen, waarna de dosis kan worden verhoogd tot 7 mg per dag

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J Biol Chem 264: 12826-12829, 1989

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