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New generation biomarkers and multi-omic approaches MASLD has a globally increasing prevalence and has the potential to progress to its more severe form, MASH
Comprehensive monitoring should include assessment of therapeutic response and screening for potential adverse effects, particularly signs of malignancy given the angiogenic effects
obesity is starting to decline
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This association was largely explained by a reduced risk of compensated and decompensated cirrhosis (aHR: 0.85), whereas no significant effect was observed for HCC (aHR: 1.05) [60]
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