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To determine whether prevention of zinc-ATF4-ARX-induced SC--cell identity loss could improve glycemic control in SC-islets, we transplanted SC-islets into hyperglycemic mice and administered the ISR inhibitor trans-ISRIB via i.p

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TLR4-associated IRF-7 and NFB signaling act as a molecular link between androgen and metformin activities and cytokine synthesis in the PCOS endometrium

Cell Protection and Repair: By modulating cell adhesion molecules, it strengthens intercellular connections, promoting the repair of epithelial cells and connective tissue