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What warrants attention and a call to the clinic: persistent nausea beyond the first 10 days, injection site reactions that worsen rather than resolve, or any signs of systemic allergic response
10.1111/jcmm.13333 24 KillgoreJ.SmidtC.DuichL.Romero-ChapmanN.TinkerD.ReiserK.et al (1989)
Participants who completed a 36-week lead-in period showed a mean weight reduction of 20.9%, with those continuing tirzepatide reaching an overall reduction of 25.3% from baseline to week 88
Long-term use appears safe and effective
While there are some differences between small fiber neuropathy and fibromyalgia, about 40-60% of people diagnosed with fibromyalgia meet the biopsy criteria for small fiber neuropathy.[ref] Genetic connection: Read more about genetics and small fiber neuropathy Familial Mediterranean Fever (FMF) Overlapping Symptoms: FMF and fibromyalgia both involve recurrent episodes of pain, fatigue, and sometimes joint or muscle pain
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