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J Innate Immun (2016) 8(6):60116

You should always tell your provider about: Current medications and supplements Known allergies Pre-existing medical conditions When to contact your provider: If you experience a persistent headache, severe muscle weakness, or a rash that lasts longer than 24 hours, please call your provider

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The vial rubber stopper is damaged Repeated punctures through the same spot can core the rubber stopper, creating small rubber particles that fall into the solution