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Decreased levels of the reduced form of GSH in T2DM correlated with a significant increase in the levels of MDA in the plasma ( Figure 3B ) and RBCs ( Figure 3C ) from T2DM subjects when compared to healthy subjects

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4.3.3 Disulfidptosis-associated signaling pathway: Nrf2/Trx regulation in stroke Nuclear factor E2-associated factor 2 (Nrf2) is a transcription factor that binds to Kelch-like ECH-associated protein 1 (KEAP1) (Suzuki et al., 2023)

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