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It seems that the joint administration of PLEA + AFB1 could alleviate oxidative stress in the brain and improve the histological effects of AFB1 on the brain (419)
Exclusion of children with overt epilepsy minimized confounding from antiepileptic medications, allowing observed metabolomic changes to be more confidently attributed to dietary modulation [28, 29]
Without FDA approval, there's no regulatory oversight of manufacturing quality
Missing data for the trial product estimand were handled through multiple imputation using the Markov Chain Monte Carlo method, assuming that non-adherent participants would have responded similarly to adherent participants within the same treatment arm
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