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In summary, the reported inactive GLP-1R crystal structure reveals a unique closed conformation of the ECD, and a deeper understanding of the conformational dynamics of GLP-1R was elaborated by EM and MD simulations
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Intravenous infusion of GLP-1 with direct recording of renal sympathetic nerve activity (RSNA) Rats were anesthetized with urethane (0.75 g/kg, i.p.) and -chloralose (70 mg/kg, i.p.)
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