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Phase I trial of HuMax-IL8 (BMS-986253), an anti-IL-8 monoclonal antibody, in patients with metastatic or unresectable solid tumors

GHK-Cu is a copper-binding tripeptide that focuses primarily on extracellular matrix remodeling, collagen I/III synthesis, and gene expression resetting

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BPC-157 is a gastric pentadecapeptide that has become famous for its healing properties

The molecules are large (polymeric DNA fragments ranging from kilodaltons into the megadalton range), highly polar, and have no realistic path across intact stratum corneum