2022 Nov 1;100(11):skac328
once stable, recheck every 6-12 months Hypoglycemia risk : While tirzepatide's glucose-lowering effect is glucose-dependent, patients with type 2 diabetes taking concurrent sulfonylureas or insulin require dose adjustments of these medications to prevent hypoglycemia Pancreatitis : Acute pancreatitis has been reported with GLP-1 receptor agonists
the risk of dehydration and AKI from gastrointestinal losses is also greater in this group, particularly in those taking diuretics or RAAS-blocking medicines
Some healthcare providers may also discuss electrolyte balance, particularly if significant fluid loss occurs, based on an individual's specific health needs
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