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It has been suggested that reactive oxygen species (ROS) play an important role in the pathogenesis of airway inflammatory diseases (32,33)

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Using receptor antagonists against NK1 and NK3 receptors in porcine tracheal explants, Philips and colleagues showed that SubP and NKB induced submucosal gland fluid flux, while NKA had no effect on the gland flux [80]

The ash content was determined by burning the sample in a muffle furnace for 10 h at 550C