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Therapeutic administration of either progranulin or soluble versions of TNFR1 or PLAD in mouse models led to beneficial results [189,190,191], opening the door to another type of non-antibody anti-TNF - drugs [23, 192]

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Examples include myopia (nearsightedness), hyperopia (farsightedness), presbyopia (age-related farsightedness), and astigmatism (where the cornea or lens of the eye has an egg-shaped curvature instead of spherical)