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In detail, activated clonally expanded CD8 + T cells, which have a transcriptional profile related to chronic antigenic stimulation, significantly accumulate in the livers of MASH mice and patients with MASH-related cirrhosis, indicating a potential role for antigen activation of CD8 + T cells in MASH pathogenesis [80]
The improvement was most pronounced in cases of moderate nausea, which aligns closely with the type of nausea most semaglutide users experience
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