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In studies of people with type 2 diabetes, Mounjaro was better than Ozempic at lowering HbA1C, with reductions of around 2.3% and supporting weight loss, with participants shedding 15.3% of body weight, depending on the dose
It influences fat storage and metabolism
Diabetes Metab Res Rev 2025;41:e70037.PubMedPMC 81
In the randomized Semaglutide Treatment Effect in People with Obesity (STEP) 1 trial (intent to treat: 1,961 adults with overweight or obesity without T2D), once-weekly subcutaneous semaglutide 2.4 mg resulted in greater weight loss compared with placebo over a 68-week period (estimated treatment difference 12.4 percentage points, 95% confidence interval (CI) 13.4, 11.5
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