scRNA-seq analysis of AS-derived endometrial organoids has identified significant gene expression alterations, particularly in WNT and NOTCH signaling pathways, mirroring changes seen in the in vivo endometrium [79]
What makes it different and powerful is the synergy between its various components
Moreover, wild-type BRCA1/2 ovarian tumors with mutations in RAD51, ATM, and ATR had higher predicted neoantigen levels than HR-proficient tumors [59, 60]
Consequently, cationic CPPs, which are better suited for cellular uptake owing to their positive charge, are more effective for the cellular delivery of CAND
Table 1 Potential therapeutic interventions targeting amino acid metabolic axes and their research progress in inflammatory or autoimmune diseases