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Acknowledgements The authors would like to acknowledge the facilities provided by the Department of Botany (CAS Phase VII), University of Calcutta, DBT-IPLS facility, University of Calcutta for confocal microscopy facility and IM would like to thank UGC under Government of India for CSIR-UGC NET fellowship scheme

ICAM-1, intercellular cell adhesion molecule-1

The FLOW study particularly indicated that semaglutide decreased the progression to end-stage renal disease by 24% in individuals with diabetic kidney disease (Rossing et al

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Additionally, in other studies of CAG, metabolomics analysis had been conducted using samples, such as serum and urine, and many CAG biomarkers had been identified