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In people with T2D, retatrutide (0.5 to 12 mg) led to substantial reductions in bodyweight and HbA1c compared to both placebo and dulaglutide 1.5 mg in a phase 2 trial [67]

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Abstract Background/Objectives Glucagon-like peptide-1 receptor agonist medications (GLP-1s) are effective for weight loss, but when people discontinue them, they tend to regain weight