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In summary, these findings indicated that oxalate exposure upregulated ferroptosis driver ACSL4 and downregulated inhibitors like GPX4 and FSP1, leading to lipid peroxidation and mitochondrial dysfunction, which collectively triggered ferroptosis in renal tubular cells

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Tirzepatide: A Dual-Action Approach to Weight Loss Tirzepatide is a dual receptor agonist, meaning it activates both GLP-1 and GIP (Glucose-Dependent Insulinotropic Polypeptide) receptors

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