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Uptake into intestinal epithelial and immune cells appears to be mediated substantially by the PepT1 oligopeptide transporter, which gives it genuine tissue selectivity for gut mucosa
Ben-Meir A, Burstein E, Borrego-Alvarez A, et al
Frequency in the research framing runs from once to three times per day , and this is where the compounds pharmacology does the talking: Ipamorelin produces a relatively short GH pulse, so a single daily dose places one pulse while two or three daily doses place multiple pulses across the day
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