No comparable human dosing data exists for the BPC-157 and TB-500 combination, and these isolated findings do not establish safety for any combined use
While the IOM had based B12 needs on the amount required to correct hematological parameters for people with pernicious anemia, the EFSA had almost 20 more years of research to draw on, and concluded that the most suitable approach was basing needs on biomarkers (serum B12, holotranscobalamin, MMA, and homocysteine)
Results may vary depending on individual metabolism, baseline nutrient levels, and overall health
Animal studies show systemic effects at lower absolute doses via injection
Hypogonadism has also been linked to osteoporosis, cardiovascular disease, and early onset diabetes [1]