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The FDA-labeled escalation is: Days 130: 1.5 mg once daily Days 3160: 4 mg once daily Days 6190: 9 mg once daily Day 91 and onward (maintenance): 25 mg once daily Also in the label: If a patient doesnt tolerate a dose, clinicians may delay escalation

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When combined with caloric restriction, they support an additional 2-4 pounds of weight loss per month compared to diet alone

It is important to recognise that cognitive symptoms can arise from multiple sources, including the underlying conditions being treated (diabetes itself can affect cognition), concurrent medications, lifestyle factors, or coincidental health issues