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Incretin mimetics provide a pharmacological stimulus to insulin secretion and elicit other GLP-1-receptor-mediated activity as drugs, but are typically introduced at much higher concentrations compared with physiological levels of GLP-1 [65, 66]
The USPTOs proposed rule would have required that if any claim of a patent subject to a terminal disclaimer is found invalid in a final court decision, every other patent tied to that patent by a terminal disclaimer would become unenforceable
The neutrophil-activating protein of Helicobacter pylori (HP-NAP) activates the MAPK pathway in human neutrophils
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The pharmacokinetic study found a C_max of 4 h and a terminal half-life of 12.6 h, and statistically significant improvements in motor (MDS-UPDRS), non-motor (NMSQuest) functions, as well as in the quality of life were observed
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