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In clinical use, significant side effects are uncommon, and the vast majority of patients tolerate the therapy without problems

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Ghadimi D, de Vrese M, Heller KJ, Schrezenmeir J (2010) Lactic acid bacteria enhance autophagic ability of mononuclear phagocytes by increasing Th1 autophagy-promoting cytokine (IFN-) and nitric oxide (NO) levels and reducing Th2 autophagy-restraining cytokines (IL-4 and IL-13) in response to Mycobacterium tuberculosis antigen

However, it's important to consult with a healthcare provider before starting any new supplement regimen, especially if you have existing health conditions, take medications, or are pregnant or breastfeeding

doi: 10.1152/japplphysiol.00945.2010