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Vegans and vegetarians: Since B12 is primarily found in animal products, supplementation is often necessary

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however, two additional legumes (broad bean and lupine) appear to lack this glutathione analog in all assayed tissue types (Matamoros et al., For biosynthesis of glutathione and homoglutathione share a common first reaction, i.e., the synthesis of -glutamylcysteine, but the chemical diversity results from altered specificity for the nucleophilic amino acid in the second reaction of the pathway