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They can build better eating and exercise habits, then revisit prescription options later if needed
While no direct drug-drug interaction has been identified, combining the two may amplify certain effects - particularly appetite suppression, nausea changes, or gastrointestinal sensitivity
The EXSCEL trial (Bethel et al., 2020) and LEADER trial (Marso et al., 2016) investigated the effect of exenatide and liraglutide, respectively, on microvascular and cardiovascular outcomes in patients with type 2 diabetes
10.1056/NEJMoa2403347 75 PerlS
The Placebo Effect and Psychological Factors Some reported benefits might stem from the placebo effect, where the belief in the treatment's efficacy leads to perceived improvements
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