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All experiments were approved by the Animal Research Committee of the University of Fukui (Approval number: 28091) and conducted in accordance with the University of Fukui regulations on animal experiments and Association for Research in Vision and Ophthalmology Statement for the Use of Animals in Ophthalmic and Vision Research

Patients with certain medical conditions, including MEN2, medullary thyroid carcinoma, or pregnancy, may not be eligible

However, once diagnosed it presents a difficult management problem in patients suffering from pernicious anemia, as there is no substitute

So these were the kinds of explanations people put up