GLP-1 Medications with a simple generic name of "semaglutide", "liraglutide", "tirzepatide", "dulaglutide", "exenatide", "exenatide microspheres", or "insulin degludec/liraglutide" and at least one of: A pharmaceutical class of "ANTI-OBESITY GLUCAGON-LIKE PEPTIDE-1 RECEP AGONIST" or "ANTIHYPERGLYCEMIC - INCRETIN MIMETICS COMBINATION" A pharmaceutical class that contains "GLP-1" A pharmaceutical subclass that contains the text "GLP-1"
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Less Common but Serious Side Effects Some less common but more serious GLP-1 side effects are worth being aware of: Pancreatitis (inflammation of the pancreas) Gallbladder problems (including gallstones) Acute kidney injury (usually as a result of severe dehydration from vomiting or diarrhea) Diabetic retinopathy worsening (particularly in patients with rapid improvement in blood sugar control) Hypoglycemia (when combined with other diabetes medications like sulfonylureas or insulin) All GLP-1 medications also carry a warning regarding a theoretical risk of medullary thyroid carcinoma, based on animal studies
Immediate medical attention is necessary if these symptoms occur
Possibly the IRS treats prescribed compounded medicines as Section 213(d) qualified expenses when they are medical care, but some HRA plans now explicitly exclude compounded GLP-1s and FSA/HSA administrators may require additional substantiation