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We've seen a focus on precursors like N-acetylcysteine (NAC), which provide the building blocks for glutathione synthesis
The 4mg tier is also the lowest maintenance dose being tested in the Phase 3 TRIUMPH program, which signals that the sponsor considers it the minimum effective dose for a regulatory filing
Chitalia, A
We found that inhibiting IDH1 mutation-derived 2-hydroxyglutaric acid (2-HG) significantly restored HEXB expression in IDH1 mutant glioma cells (Fig
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