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Several preclinical studies have shown that Quer in the myocardium can enhance the GSH antioxidant system by regulating multiple upstream molecular targets, such as peroxisome proliferator-activated receptor-gamma (PPAR-), phosphatidylinositide 3-kinase (PI3K)/serine/threonine kinase (AKT), and Nrf2 [120, 123, 124]
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[329] In March 2026, Cardi entered a multi-year partnership with stevia-based beverage company Zevia as a brand ambassador and shareholder
However, the absence of muscle cramps from official labeling does not definitively exclude the possibility of an association, as post-marketing surveillance and real-world clinical experience sometimes reveal adverse effects not detected in controlled trial settings
