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doi: 10.1186/s12920-024-01861-3 43 KnezevicJ.StarchlC.Tmava BerishaA.AmreinK

Epitalon has been shown to modulate multiple circadian genes, including Clock, Csnk1e, and Cry2

In vitro study corroborated that the suppression of the ROS/TXNIP/HIF-1 pathway, which was presumably associated with the mitochondrial dysfunction in ferroptosis, fosters the ratio of retina-specific Treg cells, notably attenuating ocular inflammation and optic disc edema (54)