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In two participants, there was incidentally found progression of clinically stable or regressed retinopathy (one episode of proliferative retinopathy during placebo use and one nonproliferative sequela during semaglutide use)

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While the precise mechanisms underlying these cardiovascular benefits are not yet fully understood, Liraglutides ability to improve blood sugar control, reduce blood pressure, and positively impact body weight likely contributes to its favorable cardiovascular outcomes

[1] The use of anti-nausea medications (e.g., ondansetron) prior to administration of bremelanotide may help to reduce the nausea

Se ha demostrado que los AR GLP-1 reducen modestamente el colesterol total, el colesterol LDL y los triglicridos, lo que sugiere un posible efecto beneficioso