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Obesity is a major risk factor for high blood pressure, so by promoting weight loss, semaglutide often leads to a meaningful drop in blood pressure, including for people whose readings remain high despite taking blood pressure medications
Semaglutide (Ozempic/Wegovy) raises resting heart rate by approximately 14 bpm, and tirzepatide (Mounjaro/Zepbound) by approximately 24 bpm
Novo Nordisks response suggested that those figures did not take into account the resources spent in the years of research and development, stating it spent $10 billion on development of GLP-1 drugs
References 1 ParikhKAntanaviciuteAFawkner-CorbettDJagielowiczMAulicinoALagerholmCet al
L-carnitine supplementation increases trimethylamine-N-oxide but not markers of atherosclerosis in healthy aged women
