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263 Similarly, in HCC, the oncofetal protein CLDN6 competes with TJP2 for YAP1 binding via its PDZ domain, displacing YAP1 from tight junctions and facilitating its nuclear localization
However, more extensive studies must be conducted to confirm its long-term impact
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Recent Trends in GLP-1 Use and Spending in Medicare Ahead of the Trump administrations planned expansion of Medicare coverage for GLP-1s to treat obesity through temporary models and the availability of Medicares negotiated price for certain GLP-1 products beginning in 2027, new data from the Centers for Medicare & Medicaid Services (CMS) shows that use and spending for these drugs under Medicare has grown substantially in recent years, reflecting their demonstrated effectiveness at treating type 2 diabetes and other conditions
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