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Another crucial study, the STEP 4 trial, evaluated the initial dose-escalation run-in period
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For persistent symptoms, prescription medications such as lubiprostone, linaclotide, plecanatide, or prucalopride may be appropriate for some patients after medical evaluation
Because studies show the medication is a large molecule, it may not transfer much, but without research, experts advise against using it while breastfeeding
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