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Lean mass preservation remains relatively good because AOD 9604 selectively targets adipose tissue while tirzepatide maintains favorable lean-to-fat loss ratios
By blocking NNMT, you're keeping visceral fat cells in a more reactive state even as overall caloric restriction continues
Those with ongoing fatigue, neurological symptoms, or high stress may require more frequent intervals
Meanwhile, NNMTi treatment significantly increased energy expenditure in mice, an effect closely related to elevated NAD levels following NNMT inhibition
If you are taking any medications, consult your doctor before use
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