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Mutations in C9orf72 result in aberrant RNA repeats that trap proteins such as TDP-43, causing RNA metabolism to be disrupted and toxic dipeptide repeat proteins (DPRs) to be produced
A peptide can only be considered best if it performs well across key metabolic variables: Appetite reduction Energy expenditure Insulin sensitivity Lean mass preservation Visceral fat targeting Side effect tolerability in research settings Single-pathway peptides often excel in one of these areas
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