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Iron metabolism Membrane lipid peroxidation with PUFA tails requires the involvement of the labile iron pool, which accelerates the Fenton reaction (Fe 2+ + HOOHFe 3+ + OH + OH ), as well as iron-dependent enzymes such as lipoxygenase and cytochrome P450 oxidoreductase [28]
Metformin limits osteoarthritis development and progression through activation of AMPK signalling
It is a type of medication that also helps patients with type 2 diabetes
5, 2011, pp
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