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Additionally, exploring combination therapies or repurposing existing drugs to counteract known resistance mechanisms may offer promising avenues for managing resistant Leishmani a cases
It differs from the native 70 residue growth factor in two respects: glutamate at position 3 is replaced by arginine, and a hydrophobic 13 residue extension (MFPAMPLLSLFVN) is fused to the N-terminus
Enzymatic control of cysteinyl thiol switches in proteins
doi: 10.1016/j.micpath.2016.11.025 30 RamotBSzeinbergAAdamAShebaCGafniD
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