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When Vitamin C is taken orally, it goes through the digestive system where much of it is lost due to absorption limitations
Most of them exert redox potential control and oxidoreductase function, e.g., glutathione peroxidase (GPX/GPx) 14 and 6, thioredoxin reductase (TXNRD/TrxR) 13, and selenoprotein R/methionine sulfoxide reductase B1 (SELENOR/SelR/MSRB1)
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Only recurrent patients were used for this analysis
Whooten R, Schmitt J, Schwartz A (2018) Endocrine manifestations of Down syndrome
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