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Nonalcoholic liver disease (nonalcoholic steatohepatitis, NASH)

The aim of this study was to evaluate the performance of the Sentosa SQ HCV Genotyping Assay, a novel deep sequencing-based assay targeting the HCV nonstructural 5B (NS5B) region, in clinical samples from patients with an indication for anti-HCV therapy

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Together, our data suggest that the distinct steady-state localizations of Go-Nt 7 and MGNC-Nt 7 are due to the differential substrate specificities of PM- and Golgi-localized enzymatically active zDHHCs, which can further be differently influenced by the accessory proteins

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