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In particular, one study examined the association between CKD and homocysteine levels in the context of genetic patterns and found that homocysteine was likely to play a causative role in CKD

Previous studies have demonstrated that UPS affects the function of GMCs through AGES/RAGE, NF-B, Trim13/CHOP, Smurf1/TGR5, and Nrf2/ARE pathways

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Then, the cells were transfected with 1 g of pDNA3.1 plasmid using a 1:3 DNA: PEI ratio for 23 hours

J Biol Chem 275: 2179721800 Le A, Cooper CR, Gouw AM, Dinavahi R, Maitra A, Deck LM, Royer RE, Vander Jagt DL, Semenza GL, Dang CV (2010) Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression