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Recent evidence suggests that AST may interfere with these pathogenic processes by reducing amyloid- aggregation and attenuating tau hyperphosphorylation in Alzheimers models, thereby mitigating protein-induced neuronal toxicity

Liver (hepatic) and kidney safety considerations are equally important, since some supplements that undergo hepatic metabolism or renal excretion can accumulate or interact with chemotherapeutic drugs leading to hepatotoxicity (e.g., kava, high-dose green tea extract) or nephrotoxicity in patients who already suffer from impaired organ function or taking chemotherapy agents known to be nephrotoxic such as cisplatin (208, 209)

Hu G, Qiao Q, Tuomilehto J, Balkau B, Borch-Johnsen K, Pyorala K

As with any viral active, though, it's worth separating the buzz from the evidence before it earns a place in your routine