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Severe deficiency can contribute to fatty liver changes, which is one reason choline gets framed as liver support. Details are summarized in the NIH ODS Choline fact sheet for health professionals

However, many celebrities have praised the drugs, including Winfrey, who left her longtime position on the board of WeightWatchers in March 2024 after revealing that she used a weight-loss medication

The delayed gastric emptying is a core mechanism of how these medications work, but it does mean your digestive system needs more time to process food