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Unlike metformin, which has documented effects on ileal B12 uptake, GLP-1 and GIP receptor agonists do not directly affect the intrinsic factor-B12 complex or terminal ileum absorption

According to data from Grand View Research, the global peptide market was valued at $140.86 billion in 2025 and is projected to reach $294.58 billion by 2033

The FOXO4p53 axis in senescence p53 is a major tumour suppressor and master regulator of cellular stress responses: DNA damage, oxidative stress, oncogene activation

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Biochemistry 30 , 74777483 (1991)